Coronary sinus rhythm induced by selective use of catecholamine in the in situ dog heart.

نویسندگان

  • S Chiba
  • K Hashimoto
چکیده

The selective administration of dopamine, norepinephrine, epinephrine and isoproterenol, into the coronary sinus region of the dog heart produced so-called coronary sinus rhythm, indicating the appearance of deep inverted P waves and frequently accompanied by an acceleration of pacemaker activity of the coronary sinus region. These effects of catecholamines were not influenced by atropine and tetrodotoxin but were blocked by propranolol. The coronary sinus rhythm was easily produced by suppression of SA nodal pacemaker activity. Coronary sinus rhythm may be readily elicited if the coronary sinus area is excited by adrenergic stimuli or if the SA node is suppressed by cholinergic excitation.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of aminophylline on the SA node of the dog heart in situ.

CHIBA, S. and HASHIM0TO, K. Effect of Aminophylline on the SA Node of the Dog Heart in situ. Tohoku J. exp. Med., 1973, 109 (2), 203-204 -The perfusion of the sinus node artery in 9 dogs in situ was performed. The selective injection of aminophylline into the sinus node artery induced a positive chronotropic response. The positive chronotropic response to aminophylline was suppressed not only b...

متن کامل

Correlation between the response of the heart to sympathetic stimulation and the release of endogenous catecholamines into the coronary sinus of the dog.

The relationship between the increase in catecholamine levels of the coronary sinus blood and the amplitude of various cardiac responses to adrenergic nerve stimulation was studied in anesthetized dogs. Plasma catecholamine levels in both coronary sinus and aortic blood were measured by a modification of the radiometric enzymatic assay for tissue catecholamines and were found to be 0.622 plus o...

متن کامل

Oscillatory nature of AV nodal pacemaker activity.

The perfusion of the AV node artery in dog heart in vivo was performed. After destroying the sinoatrial node by selective injection of ethanol into the sinus node artery, the selective administration of catecholamines into the AV node artery induced acceleration of nodal rhythm. In the course of recovery, eminent oscillatory change in the AV nodal rhythm was regularly observed. This oscillatory...

متن کامل

Concurrent atrioventricular block, sinus arrest and pneumothorax in a dog secondary to vehicle accident

In human several kinds of electrocardiographic findings have been reported in association with pneumothorax such as decreased and/or alternating QRS amplitude (electrical alternans). However, electrocardiographic changes concurrent with pneumothorax have rarely been discussed in veterinary literature. A 3-year-old male crossbreed dog was presented with a history of car accident. Thoracic au...

متن کامل

Effects of epinephrine, isoproterenol and IPS-339 on sympathetic transmission to the dog heart: evidence against the facilitatory role of presynaptic beta adrenoceptors.

The autoregulation of norepinephrine (NE) release mediated by presynaptic alpha and beta adrenoceptors on sympathetic nerve terminals in the heart of pentobarbital-anesthetized dog was studied. NE overflow elicited by left cardiac sympathetic nerve stimulation was determined from the coronary sinus blood, by using high-performance liquid chromatography with electrochemical detection. Intracoron...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Japanese heart journal

دوره 13 5  شماره 

صفحات  -

تاریخ انتشار 1972